Ionis Pharmaceuticals (IONS) and Biogen (BIIB) Report Updates on tofersen Phase 3 VALOR study in SOD1-ALS
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Ionis' partner Biogen provides update on tofersen Phase 3 VALOR study in SOD1-ALS
October 17, 2021 4:20 PM EDTCARLSBAD, Calif., Oct. 17, 2021 /PRNewswire/ --Â Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) partner Biogen today announced topline results from its placebo-controlled pivotal Phase 3 VALOR study of tofersen (BIIB067), an investigational antisense medicine being evaluated for people with superoxide dismutase 1 (SOD1) amyotrophic lateral sclerosis (ALS). While tofersen did not meet the primary endpoint of change from baseline to week 28 in the Revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), trends favoring tofersen were seen across multiple secondary and exploratory measures of disease activity and clinical function.
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