Notable Holders of OPKO HEALTH, Inc. (OPK)
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* Does Not Fully Represent All Holders
| Fund | Title | Shares | % Owned | Source |
|---|---|---|---|---|
| VANGUARD GROUP INC | COM | 39,310,784 | 9.50% | 13F |
| BlackRock Fund Advisors | COM | 11,329,837 | 2.74% | 13F |
| Aletheia Research & Management, Inc | COM | 9,619,877 | 2.33% | 13F |
| BlackRock Institutional Trust Company, N.A. | COM | 9,496,914 | 2.30% | 13F |
| STATE STREET CORP | COM | 9,306,684 | 2.25% | 13F |
| GEODE CAPITAL MANAGEMENT LLC | COM | 8,742,614 | 2.11% | 13F |
| D. E. Shaw & Co., INC. | COM | 5,703,425 | 1.38% | 13F |
| SCHWAB CHARLES INVESTMENT MANAGEMENT INC | COM | 5,144,840 | 1.24% | 13F |
| NORTHERN TRUST CORP | COM | 5,034,255 | 1.22% | 13F |
| MILLENNIUM MANAGEMENT LLC | COM | 4,326,865 | 1.05% | 13F |
| ORACLE INVESTMENT MANAGEMENT INC | COM | 4,242,465 | 1.03% | 13F |
| DIMENSIONAL FUND ADVISORS LP | COM | 3,754,290 | 0.91% | 13F |
| Goldman Sachs Asset Management, L.P. | CMN | 2,909,499 | 0.70% | 13F |
| Nuveen Asset Management, LLC | COM | 2,678,175 | 0.65% | 13F |
| ING INVESTMENT MANAGEMENT LLC | COM | 2,109,434 | 0.51% | 13F |
| MADISON SQUARE INVESTORS LLC. | COM | 2,051,732 | 0.50% | 13F |
| TWO SIGMA INVESTMENTS LLC | COM | 1,594,465 | 0.39% | 13F |
| CITIGROUP INC | COM | 1,549,582 | 0.37% | 13F |
| TWO SIGMA ADVISERS, LLC | COM | 1,439,197 | 0.35% | 13F |
| UBS Group AG | COM | 1,413,300 | 0.34% | 13F |
| NORDEA INVESTMENT MANAGEMENT AB | COM | 1,236,959 | 0.30% | 13F |
| Assenagon Asset Management S.A. | COM | 1,221,953 | 0.30% | 13F |
| Numerai GP LLC | COM | 1,192,116 | 0.29% | 13F |
| Connor, Clark & Lunn Investment Management Ltd. | COM | 1,092,121 | 0.26% | 13F |
| TEACHERS ADVISORS INC | CS | 1,054,894 | 0.25% | 13F |
| WOLVERINE ASSET MANAGEMENT LLC (PUT) | COM | 1,000,100 | 0.24% | 13F |
| AWM Investment Company, Inc. | common | 1,000,000 | 0.24% | 13F |
| JACOBS LEVY EQUITY MANAGEMENT INC | COM | 956,571 | 0.23% | 13F |
| BLACKROCK ADVISORS LLC | COM | 945,715 | 0.23% | 13F |
| Swiss National Bank | COM | 925,255 | 0.22% | 13F |
| Intrinsic Edge Capital Management LLC | COM | 900,000 | 0.22% | 13F |
| BARCLAYS PLC | COM | 768,078 | 0.19% | 13F |
| JUPITER ASSET MANAGEMENT LTD | COM | 765,198 | 0.18% | 13F |
| GROUP ONE TRADING, L.P. (CALL) | COM | 744,800 | 0.18% | 13F |
| TIAA CREF INVESTMENT MANAGEMENT LLC | CS | 736,887 | 0.18% | 13F |
| Marshall Wace LLP | COMMON STOCK | 693,733 | 0.17% | 13F |
| CREDIT SUISSE AG/ | COM | 651,530 | 0.16% | 13F |
| RHUMBLINE ADVISERS | COM | 648,704 | 0.16% | 13F |
| ROYAL BANK OF CANADA \ | COM | 638,730 | 0.15% | 13F |
| Hennion & Walsh Asset Management, Inc. | COM | 627,420 | 0.15% | 13F |
| Marshall Wace North America, L.P. | COMMON STOCK | 591,074 | 0.14% | 13F |
| ALLIANCEBERNSTEIN L.P. | COM | 570,109 | 0.14% | 13F |
| BlackRock Group LTD | COM | 568,477 | 0.14% | 13F |
| PUTNAM INVESTMENT MANAGEMENT LLC | 565,931 | 0.14% | 13F | |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | COMMON STOCK | 508,114 | 0.12% | 13F |
| Invesco Ltd. | COM | 440,515 | 0.11% | 13F |
| UBS GLOBAL ASSET MANAGEMENT AMERICAS INC | EQUITY US CM | 440,282 | 0.11% | 13F |
| PRICE T ROWE ASSOCIATES INC /MD/ | COMM STK | 428,310 | 0.10% | 13F |
| LEGAL & GENERAL GROUP PLC | COM | 422,811 | 0.10% | 13F |
| COMMONWEALTH EQUITY SERVICES, LLC. | COM | 414,011 | 0.10% | 13F |
| Capula Management Ltd | COM | 372,680 | 0.09% | 13F |
| STATE OF WISCONSIN INVESTMENT BOARD | COM | 358,284 | 0.09% | 13F |
| Zebra Capital Management, LLC | COM | 351,745 | 0.09% | 13F |
| HRT FINANCIAL LLC | COM | 344,701 | 0.08% | 13F |
| Engineers Gate Manager LP | COM | 322,094 | 0.08% | 13F |
| RENAISSANCE TECHNOLOGIES LLC | COM | 321,353 | 0.08% | 13F |
| PICTET ASSET MANAGEMENT LTD | COM | 301,030 | 0.07% | 13F |
| UBS AG | COM | 287,663 | 0.07% | 13F |
| Verition Fund Management LLC | COM | 264,700 | 0.06% | 13F |
| BlackRock Investment Management, LLC | COM | 257,123 | 0.06% | 13F |
| ETF MANAGERS GROUP, LLC | Common Stock | 256,528 | 0.06% | 13F |
| TUDOR INVESTMENT CORP ET AL | Equity | 244,821 | 0.06% | 13F |
| MANUFACTURERES LIFE INSURANCE CO | COM | 241,217 | 0.06% | 13F |
| AE Wealth Management LLC | COM | 232,405 | 0.06% | 13F |
| GTS SECURITIES LLC (CALL) | COM | 231,200 | 0.06% | 13F |
| DEUTSCHE BANK AG\ | COM | 228,871 | 0.06% | 13F |
| MetLife Investment Advisors, LLC | COM | 211,348 | 0.05% | 13F |
| HENDERSON GROUP PLC | COM | 208,449 | 0.05% | 13F |
| AMERICAN INTERNATIONAL GROUP INC | COM | 200,496 | 0.05% | 13F |
| GAMCO Investors | EQUITY | 200,000 | 0.05% | 13F |
| FRANKLIN RESOURCES INC | COM | 193,867 | 0.05% | 13F |
| Graham Capital Management, L.P. | COM | 188,061 | 0.05% | 13F |
| WELLS FARGO & CO/MN | COM | 185,805 | 0.04% | 13F |
| GABELLI FUNDS LLC | EQUITY | 185,000 | 0.04% | 13F |
| X-Square Capital, LLC | US HLTHCARE ETF | 180,070 | 0.04% | 13F |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | COM | 176,020 | 0.04% | 13F |
| PARAMETRIC PORTFOLIO ASSOCIATES | Common Stock | 175,466 | 0.04% | 13F |
| OCCUDO QUANTITATIVE STRATEGIES LP | COM | 173,089 | 0.04% | 13F |
| Teton Advisors, Inc. | EQUITY | 170,000 | 0.04% | 13F |
| CAPITAL ADVISORS INC/OK | COM | 164,625 | 0.04% | 13F |
| WEISS GEORGE A | COM | 163,856 | 0.04% | 13F |
| Second Half Financial Partners, LLC | COM | 158,053 | 0.04% | 13F |
| Allianz Asset Management AG | COM | 150,279 | 0.04% | 13F |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | COM | 144,928 | 0.04% | 13F |
| JANE STREET GROUP, LLC | COM | 141,775 | 0.03% | 13F |
| Van Eck | COM | 141,180 | 0.03% | 13F |
| LADENBURG THALMANN FINANCIAL SERVICES INC | COM | 134,624 | 0.03% | 13F |
| Cambridge Investment Research Advisors, Inc. | HEALTH INC COM | 133,325 | 0.03% | 13F |
| WILBANKS SMITH & THOMAS ASSET MANAGEMENT LLC | COM | 131,380 | 0.03% | 13F |
| NEW YORK STATE COMMON RETIREMENT FUND | Common Stock | 127,900 | 0.03% | 13F |
| Arizona State Retirement System | COM | 119,362 | 0.03% | 13F |
| Csenge Advisory Group | COM | 117,000 | 0.03% | 13F |
| AMERIPRISE FINANCIAL INC | COM | 110,691 | 0.03% | 13F |
| IndexIQ Advisors LLC | COM | 109,868 | 0.03% | 13F |
| BLAIR WILLIAM & CO/IL | COM | 109,787 | 0.03% | 13F |
| PRUDENTIAL FINANCIAL INC | COM | 104,996 | 0.03% | 13F |
| BNP PARIBAS ARBITRAGE, SA | Equity | 104,913 | 0.03% | 13F |
| Aperio Group, LLC | COM | 100,821 | 0.02% | 13F |
| INTREPID CAPITAL MANAGEMENT INC | COM | 100,000 | 0.02% | 13F |
| Quantbot Technologies LLC | COM | 99,886 | 0.02% | 13F |
| SOCIETE GENERALE | COM | 98,935 | 0.02% | 13F |
| Creative Planning | COM | 98,745 | 0.02% | 13F |
| DAVIDSON TRUST CO/PA/ | COM | 90,000 | 0.02% | 13F |
| Handelsbanken Fonder AB | COM | 86,121 | 0.02% | 13F |
| Cubist Systematic Strategies, LLC | COM | 84,739 | 0.02% | 13F |
| HOLLENCREST SECURITIES LLC | Stock | 83,980 | 0.02% | 13F |
| KCG Holdings, Inc. | COM | 82,453 | 0.02% | 13F |
| RPg Family Wealth Advisory, LLC | COM | 80,330 | 0.02% | 13F |
| SG Americas Securities, LLC | COM | 77,560 | 0.02% | 13F |
| Trellus Management Company, LLC | COM | 74,388 | 0.02% | 13F |
| Commonwealth Equity Services, Inc | COM | 74,061 | 0.02% | 13F |
| CHICAGO EQUITY PARTNERS LLC | COM | 73,644 | 0.02% | 13F |
| Delek Group, Ltd. | COM | 73,000 | 0.02% | 13F |
| Jump Trading, LLC | Common Stock | 71,900 | 0.02% | 13F |
| SPOT TRADING L.L.C. (PUT) | COM | 70,500 | 0.02% | 13F |
| BDO Wealth Advisors, LLC | COM | 70,000 | 0.02% | 13F |
| Emerald Acquisition Ltd. | Common Stocks | 65,945 | 0.02% | 13F |
| PICTET ASSET MANAGEMENT SA | COM | 65,495 | 0.02% | 13F |
| SHELL ASSET MANAGEMENT CO | COM | 64,713 | 0.02% | 13F |
| Gupta Wealth Management LLC | COM | 62,450 | 0.02% | 13F |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | COM | 61,502 | 0.01% | 13F |
| Amundi | COM | 60,662 | 0.01% | 13F |
| Schonfeld Strategic Advisors LLC | COM | 58,157 | 0.01% | 13F |
| State of Wyoming | COM | 57,889 | 0.01% | 13F |
| 360 Financial, Inc. | COM | 56,960 | 0.01% | 13F |
| Xact Kapitalforvaltning AB | COM | 55,821 | 0.01% | 13F |
| Zurcher Kantonalbank (Zurich Cantonalbank) | COM | 55,140 | 0.01% | 13F |
| TWO SIGMA SECURITIES, LLC | COM | 55,026 | 0.01% | 13F |
| Lehman Financial Resources, Inc. | COM | 54,800 | 0.01% | 13F |
| Raymond James Financial Services Advisors, Inc. | COM | 53,301 | 0.01% | 13F |
| Point72 Middle East FZE | COM | 52,710 | 0.01% | 13F |
| ProShare Advisors LLC | COM | 52,461 | 0.01% | 13F |
| XTX Topco Ltd | COM | 52,368 | 0.01% | 13F |
| AHL Partners LLP | COM | 51,502 | 0.01% | 13F |
| MFC GLOBAL INVESTMENT MANAGEMENT (U.S.), LLC | COM | 51,479 | 0.01% | 13F |
| PRINCIPAL FINANCIAL GROUP INC | COM | 51,114 | 0.01% | 13F |
| KS MANAGEMENT CORP (PUT) | COM | 50,900 | 0.01% | 13F |
| TRANSCEND WEALTH COLLECTIVE, LLC | Stock | 50,850 | 0.01% | 13F |
| CAPTRUST FINANCIAL ADVISORS | Stock | 50,726 | 0.01% | 13F |
| LEVIN CAPITAL STRATEGIES, L.P. | COM | 50,000 | 0.01% | 13F |
| RAYMOND JAMES & ASSOCIATES | COM | 49,346 | 0.01% | 13F |
| VIRGINIA RETIREMENT SYSTEM | COM | 49,100 | 0.01% | 13F |
| Ethic Inc. | COM | 48,649 | 0.01% | 13F |
| Amalgamated Financial Corp. | COM | 48,211 | 0.01% | 13F |
| Manulife Asset Management (North America) Ltd | COM | 47,795 | 0.01% | 13F |
| VICTORY CAPITAL MANAGEMENT INC | COM | 45,684 | 0.01% | 13F |
| Geduld E E | COM | 45,010 | 0.01% | 13F |
| Integrated Wealth Concepts LLC | Common Stock | 44,500 | 0.01% | 13F |
| KESTRA PRIVATE WEALTH SERVICES, LLC | COM | 44,400 | 0.01% | 13F |
