PTAB again upholds TwinStrand patent challenged by Guardant Health

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TwinStrand Biosciences Announces Second U.S. Patent Trial and Appeal Board Decision Upholding All Claims of TwinStrand’s ‘127 Patent

October 15, 2026 4:01 PM EDT

Following Federal Circuit remand, the PTAB again rules in favor of the University of Washington and TwinStrand on all 30 claims of the 127 patent challenged by Guardant Health

SEATTLE--(BUSINESS WIRE)-- TwinStrand Biosciences (TwinStrand), the pioneer in Duplex Sequencing® technology, today announced that the U.S. Patent and Trademark Offices Patent Trial and Appeal Board (PTAB) has again rejected Guardant Health, Inc.s (Nasdaq: GH) challenge to a core patent underlying Duplex Sequencing. In an Oct. 14, 2026, Final Written Decision on remand from the U.S. Court of... More