Takeda launches narcolepsy drug Orzeyful in Japan and China

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Go back to Takeda launches narcolepsy drug Orzeyful in Japan and China

Takeda’s ORZEYFUL (oveporexton) Launches Simultaneously in Japan and China Giving Physicians First Access to Prescribe Novel Orexin Agonist to Patients with Narcolepsy Type 1

October 14, 2026 8:30 PM EDT

ORZEYFUL is now available in Japan and China following approvals within a month of each other by Chinas National Medical Products Administration (NMPA), the U.S. Food and Drug Administration (FDA) and Japans Ministry of Health, Labour and Welfare (MHLW)

Discovered by Takeda scientists in Japan, ORZEYFUL is the lead medicine in Takedas orexin franchise, with multiple programs for sleep-wake disorders and conditions where orexin biology plays a role

ORZEYFUL set to launch next month in the U.S., following completion of DEA scheduling; Health Authority submissions underway worldwide

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