Lilly's Jaypirca reduces disease progression risk by 45% in CLL study

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Lilly's Jaypirca (pirtobrutinib) significantly reduced the risk of disease progression or death by 45% when added to a venetoclax time-limited regimen in people with previously treated CLL/SLL

June 14, 2026 3:15 AM EDT

BRUIN CLL-322 is the first Phase 3 study to demonstrate superiority over a venetoclax-containing control arm in CLL, and, with the majority of patients previously treated with a covalent BTK inhibitor, reflects current practice patterns

These data will be highlighted in a late-breaking oral presentation at the 2026 European Hematology Association (EHA) Annual Meeting

INDIANAPOLIS, June 14, 2026 /PRNewswire/ -- Eli Lilly... More