Iovance receives FDA clearance for IL-12 tethered TIL therapy trial

Go back to Iovance receives FDA clearance for IL-12 tethered TIL therapy trial

Iovance Biotherapeutics Announces Clearance of Investigational New Drug (IND) Application for IL-12 Tethered TIL Therapy IOV-5001

June 1, 2026 7:30 AM EDT

Next-Generation Platform Expands into Solid Tumors 
Representing 100,000+ U.S. Deaths Annually

SAN CARLOS, Calif., June 01, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a commercial biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer, today announced allowance to proceed from the U.S. Food and Drug Administration (FDA) for the investigational new drug (IND) application for a Phase 1/2 basket trial of IOV-5001, a next-generation interleukin-12 (IL-12) tethered TIL therapy.

The Phase 1/2 trial will begin... More