enGene reports 54% response rate in bladder cancer gene therapy trial

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enGene Announces Updated Interim Results From LEGEND Pivotal Cohort

May 7, 2026 7:00 AM EDT

54% complete response (CR) rate at any time; 43% sixmonth CR rate

Low rate of progression to muscle-invasive or higher disease (3.2%)

Low percentage of patients experienced treatment-related adverse events (TRAEs) (55%), nearly all of which were mild

Low percentage of patients experienced TRAEs leading to treatment interruption (2.4%) or discontinuation (2.4%)

Kaplan-Meier estimate of 12-month CR rate is 25%

enGene to host webcast to discuss results today, May 7, 2026, at 8:00 a.m. ET

BOSTON & MONTREAL--(BUSINESS WIRE)-- enGene Therapeutics Inc.... More