AstraZeneca's BREZTRI wins US approval for asthma treatment

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BREZTRI approved in the US for asthma as first and only triple therapy for patients 12 years of age and older

April 28, 2026 7:00 AM EDT

Approval based on KALOS and LOGOS Phase III trials demonstrating statistically significant and clinically meaningful benefits of AstraZenecas single-inhaler fixed-dose triple therapy compared with inhaled dual therapy

Approval is second indication for BREZTRI beyond COPD

WILMINGTON, Del.--(BUSINESS WIRE)-- AstraZenecas fixed-dose triple-combination therapy BREZTRI Aerosphere® (budesonide/glycopyrrolate/formoterol fumarate or BGF 320/36/9.6g) has been approved in the US for the maintenance treatment of asthma in adult and pediatric patients 12 years of age and older. BREZTRI is a single-inhaler that combines the efficacy of corticosteroid/long-acting... More