Lilly's Jaypirca shows positive results in blood cancer trial

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Lilly's Jaypirca (pirtobrutinib) significantly extended progression-free survival when added to a venetoclax time-limited regimen in patients with previously treated CLL/SLL

April 13, 2026 6:45 AM EDT

BRUIN CLL-322 is the first Phase 3 readout in CLL to utilize and outperform a venetoclax-containing control arm

This trial predominantly enrolled a patient population previously treated with covalent BTK inhibitors, highly relevant to current practice

These results mark the fourth positive Phase 3 study of pirtobrutinib in CLL

INDIANAPOLIS, April 13, 2026 /PRNewswire/ -- Eli Lilly and Company (NYSE:... More