Ascendis shows combination therapy benefits in achondroplasia trial

Go back to Ascendis shows combination therapy benefits in achondroplasia trial

New Data from Week 52 of the Ongoing COACH Trial Showed that TransCon® hGH Accelerated TransCon® CNP’s Benefits Beyond Linear Growth in Children with Achondroplasia

April 8, 2026 8:01 AM EDT

- Unprecedented improvements in arm span observed with TransCon CNP and TransCon hGH combination therapy, a measure highly meaningful to the achondroplasia community

- Enhanced improvements in spinal canal dimensions observed with TransCon CNP and TransCon hGH combination therapy compared to TransCon CNP monotherapy

- For the TransCon CNP treatment-naïve cohort, the improvement in tibial femoral angle (TFA) indicated enhanced straightening of the legs

- Children treated with long-term TransCon CNP monotherapy maintained TFA in normal range in COACH

COPENHAGEN, Denmark, April 08, 2026... More