Incyte reports 54-week data for hidradenitis suppurativa drug

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Incyte Announces New Positive 54-Week Late-Breaking Data for Povorcitinib in Hidradenitis Suppurativa at the 2026 American Academy of Dermatology (AAD) Annual Meeting

March 28, 2026 3:00 PM EDT

Phase 3 data from the STOP-HS program demonstrate povorcitinibs substantial and durable clinical efficacy through Week 54 in patients with moderate to severe hidradenitis suppurativa (HS).

Through Week 54, clinically meaningful and durable responses were observed across all groups in both STOP-HS1 and STOP-HS2, with up to 71.4% of patients achieving HiSCR50. Improvements in clinical responses across high stringent thresholds were observed, with up to 57% of participants achieving HiSCR75 and up to 29% of participants achieving HiSCR100.

Povorcitinib treatment led to consistent reductions across key inflammatory lesion types, with full resolution (ANdT=0) achieved in up to 20% of... More