AstraZeneca, Oxford aim to produce Omicron-targeted vaccine
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AstraZeneca's (AZN) Evusheld Retains Neutralizing Activity Against the Omicron Variant
December 23, 2021 5:53 AM ESTAstraZeneca's (NASDAQ: AZN) Evusheld (tixagevimab co-packaged with cilgavimab), a long-acting antibody combination for the prevention of COVID-19, retains neutralisation activity against the Omicron SARS-CoV-2 variant (B.1.1.529), according to new authentic live virus neutralisation data from both University College Oxford, UK and Washington University School of Medicine, St. Louis, US.
Evushelds Inhibitory Concentration 50 (IC50), a measure of neutralising potency of an antibody, was 273 ng/ml and 147 ng/ml in the Oxford and Washington University studies, respectively.1,2 The levels are within the range of neutralising antibody titres found in individuals who have been previously infected with... More
AstraZeneca's (AZN) Vaxzevria Significantly Boosts Antibodies Against Omicron After Third Dose
December 23, 2021 5:51 AM ESTAstraZeneca's (NASDAQ: AZN) Vaxzevria (ChAdOx1-S [Recombinant]) significantly boosted levels of antibodies against the Omicron SARS-CoV-2 variant (B.1.1.529) following a third dose booster, according to data from a new laboratory study.1
Neutralisation titres for Omicron were boosted following a third dose with Vaxzevria compared to titres after a second dose.1 The levels seen after the third dose booster were higher than the neutralising antibodies found in individuals who had been previously infected with and recovered naturally from COVID-19 (Alpha, Beta, Delta variants and original strain).1 Sera obtained from individuals one month after receiving the... More
