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Karyopharm Therapeutics (KPTI) Present Updated Phase 2 Selinexor Data in Patients with Myelofibrosis

December 13, 2021 5:23 AM EST

Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced an oral presentation highlighting updated data from the Phase 2 ESSENTIAL study, an investigator-sponsored study evaluating single-agent selinexor, a first-in-class, oral Selective Inhibitor of Nuclear Export (SINE) compound, in patients with myelofibrosis (MF) previously treated with JAK inhibition. These updated results were presented at the American Society of Hematology (ASH) 2021 Annual Meeting and Exposition taking place in Atlanta, GA on December 11-14, 2021.

"The results presented at ASH this year demonstrate that once weekly single-agent oral selinexor resulted in an... More