Pfizer files COVID-19 vaccine application to U.S. FDA

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Go back to Pfizer files COVID-19 vaccine application to U.S. FDA

Pfizer (PFE) Reports First Participant Dosing in Phase 3 Study Evaluating anti-TFPI Investigational Therapy, Marstacimab

November 23, 2020 6:46 AM EST

Pfizer Inc. (NYSE: PFE) today announced that the first participant has been dosed in the Phase 3 BASIS study of marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (anti-TFPI) being evaluated for the treatment of people with severe hemophilia A or B, with or without inhibitors.

BASIS is a global Phase 3, open-label, multicenter study that will evaluate annualized bleed rate (ABR) through 12 months on prophylaxis treatment with marstacimab, an investigational, novel subcutaneous therapy, in adolescents and adults with hemophilia A or B... More