Palomar Holdings Inc. (PLMR) Prices 5M Share Offering at $49/Sh
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Pre-Open Stock Movers 01/08: (APLT) (VSTM) (M) Higher; (EXFO) (LTHM) (RADA) Lower (more...)
January 8, 2020 9:23 AM ESTToday's Pre-Open Stock Movers:
Applied Therapeutics Inc. (NASDAQ: APLT) 22.3% HIGHER; announced positive topline results from the Pivotal Phase 2 portion of the ACTION-Galactosemia study of AT-007, a central nervous system (CNS) penetrant Aldose Reductase inhibitor, in adult Galactosemia patients. ACTION-Galactosemia is a double-blind placebo-controlled trial evaluating safety and pharmacokinetics of AT-007 in healthy volunteers, as well as safety, pharmacokinetics, and biomarker effects in adult Galactosemia patients over 28 days of once daily oral dosing. The key biomarker outcome of the study was reduction in galactitol, an aberrant toxic metabolite of galactose,... More
