AbbVie to Advance Once-Daily ABT-494 to Phase 3 in Rheumatoid Arthritis by Year-End

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AbbVie (ABBV) Announces ABT-494 Meets Primary Endpoint in Two Phase 2 Trials

September 25, 2015 7:16 AM EDT

AbbVie (NYSE: ABBV) announced results from two Phase 2 clinical trials evaluating its investigational selective JAK1 inhibitor, ABT-494, in patients with inadequate response to either methotrexate or TNF inhibitors. The clinical trials, BALANCE-I and BALANCE-II, achieved ACR20 at week 12 across all dose levels, except the... More

UPDATE: AbbVie (ABBV) to Advance ABT-494, Will Not Exercise Rights to Galapagos' (GLPG) Filgotinib

September 25, 2015 7:14 AM EDT

(Updated - September 25, 2015 7:25 AM EDT)

(Update included ticker for GLPG)

AbbVie (NYSE: ABBV), a global biopharmaceutical company, today announced that it will advance ABT-494, its internally developed investigational selective JAK1 inhibitor, to Phase 3 studies in rheumatoid arthritis. Following a thorough... More