Globe Newswire

• An additional 19 patients have been enrolled since January 2024 bringing the total to 37 of whom 25 were evaluable for efficacy
• SYS6002 (CRB-701) demonstrated 44% ORR and 78% DCR in mUC and 43% ORR and 86% DCR in cervical cancer to date at doses ≥ 1.2mg/Kg
• No dose limiting toxicities (DLTs) have been observed to date in doses up to and including 4.5 mg/Kg (cohort 7)
• Three cases of skin rash (including one grade 3) and one case of grade 1 neuropathy seen to date; all... (continue reading...)

Results from Phase 1 dose escalation trial of BDTX-1535 in GBM patients demonstrated a favorable safety and tolerability profile, and encouraging anti-tumor activity and duration of treatment

Initial data from Phase 0/1 “trigger” (“window of opportunity”) investigator-sponsored trial demonstrated BDTX-1535 achieved clinically meaningful drug levels in brain tumor tissue

CAMBRIDGE, Mass., June 01, 2024 (GLOBE NEWSWIRE) -- Black Diamond Therapeutics, Inc.... (continue reading...)

Media Release

COPENHAGEN, Denmark, and MAINZ, Germany; June 1, 2024

• Initial data from the ongoing Phase 2 trial showed a 12-month overall survival (OS) rate of 69% and median overall survival (mOS) of 17.5 months in patients with previously treated PD-L1-positive mNSCLC treated with combination of acasunlimab with pembrolizumab every six weeks
• Data from this ongoing Phase 2 study to inform the planned pivotal Phase 3 trial, which is expected to start before the end... (continue reading...)

NASSAU, The Bahamas, June 01, 2024 (GLOBE NEWSWIRE) -- OKX, a leading crypto exchange by trading volume and a leading Web3 technology company, has issued updates for June 1, 2024.

OKX Announces Position Tier Adjustments for TURBO/USDT Perpetual Futures ListingIn a continuous effort to enhance market liquidity and mitigate risks, OKX has announced that it will be making adjustments to the position tiers of its TURBO/USDT perpetual futures listing.

This action... (continue reading...)

-  WTX-124 was shown to be clinically active and generally well-tolerated in patients who were relapsed/refractory to immune checkpoint inhibitor therapy -

-  Encouraging single agent clinical activity with three objective responses, including a durable confirmed complete response -

-  Monotherapy recommended dose for expansion selected and expansion arms open for enrollment -

-  Preliminary data on WTX-124 administered to patients in combination with... (continue reading...)