| Product sales | 3.32B |
| Royalties | 136.7M |
| Other revenues | |
| Total revenues | 3.45B |
| Cost of product sales | 1.74B |
| Research and development | 511.1M |
| Selling, general and administrative | 875.6M |
| Loss/(gain) on sale of product rights | -5.7M |
| Reorganization costs | |
| Integration and acquisition costs | 284.5M |
| Total operating expenses | 3.86B |
| Operating income | -405.9M |
| Interest income | 9.3M |
| Interest expense | -186.9M |
| Other (expense)/income, net | -13.7M |
| Total other expense, net | -191.3M |
| Income before income taxes and equity in earnings of equity method investees | -597.2M |
| Income taxes | 229.6M |
| Equity in earnings of equity method investees, net of taxes | -900K |
| Net income | |
| Net income attributable to Shire plc | -386.8M |
| Earnings per ordinary share - basic | -0.43 |
| Earnings per ordinary share - diluted | |
| Earnings per ordinary share - diluted | -0.43 |
| Basic | 900.2M |
| Diluted | 900.2M |
| Net income attributable to Shire plc | |