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Karyopharm Therapeutics (KPTI) Initiates Selinexor Phase 2 in SIRRT Patients

November 10, 2014 7:22 AM EST

Karyopharm Therapeutics (Nasdaq: KPTI) announced the initiation of its Phase 2 study of Selinexor (KPT-330) in patients with Richter's transformation (SIRRT) that is relapsed after or refractory to chemotherapy. This multi-center study of Selinexor, one of the company's novel, oral Selective Inhibitor of Nuclear Export / SINE compounds, will enroll approximately 50 patients in approximately 35 sites worldwide.

This single arm, open-label, Phase 2 study will... More