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Epizyme (EPZM) Reports Publication of EPZ-5676 Data

November 6, 2014 7:34 AM EST

Epizyme (NASDAQ: EPZM) announced the publication on the website of the American Society of Hematology (ASH) of an abstract entitled The DOT1L Inhibitor EPZ-5676: Safety and Activity in Relapsed/Refractory Patients with MLL-Rearranged Leukemia. The abstract contains preliminary data from the Phase 1 trial of EPZ-5676, a potent and selective inhibitor of the DOT1L histone methyltransferase (HMT). EPZ-5676 is being developed for the treatment of acute leukemia with alterations in the MLL gene (MLL-r) or partial tandem duplications within MLL (MLL-PTD). The Company plans to present updated data... More