Wedbush Downgrades Amicus Therapeutics (FOLD) to Underperform, Sees Another 50% Slide

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Leerink Swann Cuts PT on Amicus Therapeutics (FOLD), But Remains Overall Bullilsh

December 20, 2012 12:25 PM EST

Leerink Swann cut its price target on Amicus Therapeutics (NASDAQ: FOLD) from $9 to $5 after the company reported Wednesday that Phase III study ('011) of Amigal monotherapy in Fabry disease missed its primary and secondary endpoints. However, they maintained an Outperform rating.... More

Amicus Therapeutics (FOLD), Glaxo (GSK) Report Study 011 Did Not Achieve Primary Endpoint

December 19, 2012 4:12 PM EST

Amicus Therapeutics (Nasdaq: FOLD) and GlaxoSmithKline plc (NYSE: GSK) announced the 6-month primary treatment period results from the first Phase 3 global registration study (Study 011) of investigational oral migalastat HCl monotherapy in males and females with Fabry disease who had genetic mutations identified as amenable to migalastat HCl in a cell-based assay. Study 011 randomized a total of 67 patients to receive oral migalastat HCl 150 mg or placebo on an every-other-day (QOD) dosing schedule during a 6-month, double-blind primary treatment period.

Reduction of GL-3 Substrate in Kidney Interstitial Capillaries:
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