Leerink Swann Cuts PT on Amicus Therapeutics (FOLD), But Remains Overall Bullilsh

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Wedbush Downgrades Amicus Therapeutics (FOLD) to Underperform, Sees Another 50% Slide

December 21, 2012 9:39 AM EST

Amicus Therapeutics (NASDAQ: FOLD) fell 47 percent on Thursday after its ongoing migalastat monotherapy Phase III trial did not meet the primary and a pre-defined secondary endpoint, however, one analyst thinks it goes down another 50 percent from here.

Wedbush downgraded Amicus from Neutral to... More

Amicus Therapeutics (FOLD), Glaxo (GSK) Report Study 011 Did Not Achieve Primary Endpoint

December 19, 2012 4:12 PM EST

Amicus Therapeutics (Nasdaq: FOLD) and GlaxoSmithKline plc (NYSE: GSK) announced the 6-month primary treatment period results from the first Phase 3 global registration study (Study 011) of investigational oral migalastat HCl monotherapy in males and females with Fabry disease who had genetic mutations identified as amenable to migalastat HCl in a cell-based assay. Study 011 randomized a total of 67 patients to receive oral migalastat HCl 150 mg or placebo on an every-other-day (QOD) dosing schedule during a 6-month, double-blind primary treatment period.

Reduction of GL-3 Substrate in Kidney Interstitial Capillaries:
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