Alkermes drug shows sustained narcolepsy benefits at nine months

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Alkermes’ Alixorexton Demonstrated Sustained Improvement in Wakefulness in Adults With Narcolepsy Type 1 and Type 2 in Long-Term Extension Study Interim Analysis

July 13, 2026 7:00 AM EDT

First Long-Term Study of an Orexin 2 Receptor Agonist to Demonstrate Sustained Clinically Meaningful Improvements in Wakefulness and Excessive Daytime Sleepiness for Up to Nine Months in Narcolepsy Type 1 and Type 2

Improvements in Patient-Reported Cognition and Fatigue Were Also Sustained

Alixorexton Was Generally Well Tolerated at All Doses Tested

DUBLIN--(BUSINESS WIRE)-- Alkermes plc... More