Q32 Bio reports Phase 2a trial results for alopecia areata drug

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Q32 Bio Announces Positive 36-Week Topline Results from Part B of the SIGNAL-AA Clinical Trial of Bempikibart in Alopecia Areata

July 13, 2026 6:59 AM EDT

-- Clinically meaningful efficacy data on the primary endpoint was observed with a mean percent reduction in SALT score from baseline of 35.3% in the prespecified mITT analysis --

-- 40.0% of patients achieved SALT-20 response at Week 36 in the mITT analysis and 30.3% of patients achieved SALT-20 response at Week 36 in the ITT analysis of all enrolled patients --

-- Generally well-tolerated safety profile, consistent with prior studies, with no new safety signals --

-- Bempikibart demonstrated a favorable PK, PD and ADA profile... More