Seres reports early trial data for SER-155 in cancer therapy side effect

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Seres Therapeutics Announces Early Clinical Data Showing Potential for SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis (irEC), a Frequent Adverse Reaction That Forces Many Patients to Hal

July 8, 2026 7:00 AM EDT

80% of SER-155 recipients achieved immunosuppressive-free clinical response of diarrhea (a primary symptom of irEC) at Day 15 in the Investigator-Sponsored Trial (IST) conducted by Memorial Sloan Kettering Cancer Center (MSK)

SER-155 has potential to treat irEC, a frequent side effect of immune checkpoint inhibitors (ICIs) that often causes halting of cancer treatment, without requiring treatment with systemic immunosuppressive drugs

SER-155 was well tolerated, with no drug-related serious adverse events observed

Drug pharmacology data provide confirmatory evidence of Seres live biotherapeutics operating as designed to repair the mucosal... More