Agenus reports 3-year survival data for colorectal cancer drug combo

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Agenus Reports Landmark BOT+BAL Data Showing 33% Three-Year Overall Survival in Refractory MSS Metastatic Colorectal Cancer Without Active Liver Metastases at ESMO GI 2026

July 6, 2026 7:30 AM EDT

Fully enrolled 123-patient Phase 1b cohort demonstrated 21.2-month median overall survival, 33% three-year overall survival, and a survival curve plateau beyond two years Data presented in a heavily pretreated population where durable long-term survival is rarely reported 17% of patients alive and off all systemic anticancer therapy at last follow-up Extended safety follow-up showed no new safety signals, no treatment-related deaths, and 98% resolution of immune-mediated diarrhea/colitis

LEXINGTON, Mass.--(BUSINESS... More