AstraZeneca IMFINZI combo cuts liver cancer progression risk by 30%

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IMFINZI® (durvalumab) plus IMJUDO® (tremelimumab-actl) combined with lenvatinib and TACE reduced the risk of disease progression or death by 30% in embolization-eligible unresectable liver cancer in

June 1, 2026 8:00 AM EDT

Positive overall survival trend in favor of STRIDE regimen with lenvatinib and TACE

WILMINGTON, Del.--(BUSINESS WIRE)-- Positive results from the EMERALD-3 Phase III trial showed AstraZenecas IMFINZI® (durvalumab) in combination with IMJUDO® (tremelimumab-actl), lenvatinib and transarterial chemoembolization (TACE), demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) versus TACE alone for patients with unresectable hepatocellular carcinoma (HCC) eligible for embolization. Patients in the investigational arms were treated with the STRIDE regimen (Single Tremelimumab-actl Regular Interval Durvalumab), with or without lenvatinib, prior to TACE and then in combination with... More