Astellas reports IZERVAY reduced driving eligibility loss risk in eye disease study

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IZERVAY® (avacincaptad pegol intravitreal solution) Demonstrated Increased Probability of Maintaining Driving Eligibility in Geographic Atrophy Patients

May 12, 2026 9:01 AM EDT

Pooled post hoc analysis of GATHER1 and GATHER2 showed IZERVAY® (avacincaptad pegol intravitreal solution) reduced the risk of progressing to loss of driving eligibility compared with sham over 24 months in patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD)

Encore GATHER2 open-label extension data demonstrated IZERVAY was well-tolerated, with no new safety signals, and earlier intervention with IZERVAY resulted in slowing GA with greater protection of healthy retinal tissue

NORTHBROOK, Ill.,... More