Johnson & Johnson's TREMFYA shows efficacy in perianal fistulizing Crohn's

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Johnson & Johnson study shows TREMFYA® (guselkumab) is the first and only IL-23 inhibitor to demonstrate efficacy in perianal fistulizing Crohn's disease

May 5, 2026 8:05 AM EDT

TREMFYA® demonstrated significantly higher rates of combined fistula remission complete external closure of draining fistulas and absence of fluid collection on MRI compared to placebo at Week 24

First study of its kind in 20 years for this debilitating manifestation of Crohn's disease presented as late-breaking data at Digestive Disease Week 2026

CHICAGO, May 5, 2026 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced results from the Phase 3... More