Nektar Therapeutics reports positive 52-week data for alopecia areata drug trial

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52-Week Topline Results from 16-Week Blinded Treatment Extension of REZOLVE-AA Demonstrate Deepening of Responses in Severe-to-Very-Severe Alopecia Areata with Rezpegaldesleukin

April 20, 2026 7:30 AM EDT

29% and 31% of patients in the 18 µg/kg and 24 µg/kg extension arms, respectively, achieved new SALT Score 20 from week 36 to week 52 with continued twice-monthly treatment

Increasing proportions of patients achieved clinically meaningful hair growth thresholds across numerous SALT measurements with 94% of patients completing treatment extension

Favorable safety profile with twice-monthly dosing maintained throughout 52 weeks, consistent with previously reported results

Results support advancement of rezpegaldesleukin into late-stage development in alopecia areata

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