Agenus reports mixed results from gastroesophageal cancer trial

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Agenus Reports Phase II Data Demonstrating Immune Reprogramming and Durable Survival with Botensilimab, Balstilimab and agenT-797 in PD-1 Refractory Gastroesophageal Cancer

April 17, 2026 4:43 PM EDT

First study combining botensilimab (BOT) and balstilimab (BAL) with agenT-797 in gastroesophageal cancer shows disease control rate (DCR) of 77% in patients and long-term survival beyond 20 months in a subset of heavily pretreated patients Induction strategy linked to improvement in progression-free survival (PFS) and higher survival rates at 12 and 18 months, supported by evidence of immune activation and tumor reprogramming

LEXINGTON, Mass.--(BUSINESS... More