FDA lifts partial clinical hold on MacroGenics' cancer drug study

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FDA Removes Partial Clinical Hold on MacroGenics’ LINNET Study

April 8, 2026 4:30 PM EDT

Plan to resume enrollment in clinical study of lorigerlimab in gynecologic cancers  

On track to provide mid-2026 program update 

ROCKVILLE, MD, April 08, 2026 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (NASDAQ: MGNX), a clinical-stage biopharmaceutical company focused on developing innovative antibody-based therapeutics for the treatment of cancer, today announced that the U. S. Food and Drug Administration (FDA) has removed the partial clinical hold on the Companys Phase 2 LINNET study of lorigerlimab, an investigational, bispecific DART® molecule that targets PD-1 and CTLA-4. During the partial clinical hold, previously enrolled study participants were allowed to... More