Praxis Precision Medicines reports positive trial results for epilepsy drug

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Praxis Precision Medicines Announces Positive Results from the EMBRAVE Part A Trial of Elsunersen in Patients with SCN2A Early-Onset Developmental and Epileptic Encephalopathy

April 6, 2026 8:00 AM EDT

Elsunersen demonstrated placebo-adjusted seizure reduction from baseline of 77% (p=0.015)

71% of elsunersen-treated patients achieved >50% seizure reduction by period 6, with sustained benefit observed in the open-label extension for up to one year

100% of elsunersen patients - and none on placebo - had additional improvements, including sleep, motor function, muscle tone and attention

No treatment-emergent or serious adverse events related to study drug reported

BOSTON, April 06, 2026 (GLOBE NEWSWIRE) --... More