Denali regains full rights to brain therapy after Takeda ends partnership

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Denali Therapeutics Regains Full Rights to Investigational Therapy DNL593 (PTV:PGRN) for GRN-related Frontotemporal Dementia (FTD-GRN)

April 3, 2026 1:30 PM EDT

Denali plans to continue clinical development of DNL593, which is designed to deliver progranulin to the brain using TransportVehicle technologyResults from ongoing Phase 1/2 study in patients with FTD-GRN expected by the end of 2026

SOUTH SAN FRANCISCO, Calif., April 03, 2026 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (Nasdaq: DNLI) today announced that it has received notification from Takeda of its decision to terminate the collaboration agreement between the two companies to co-develop and co-commercialize DNL593 (PTV:PGRN). The decision was... More