AstraZeneca's IMFINZI and IMJUDO combination shows progression benefit in liver cancer

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IMFINZI® (durvalumab) + IMJUDO® (tremelimumab-actl) improves PFS in early liver cancer

April 2, 2026 7:00 AM EDT

IMFINZI plus IMJUDO combined with lenvatinib and TACE demonstrated a statistically significant and clinically meaningful improvement in progression-free survival in embolization-eligible unresectable liver cancer in EMERALD-3 Phase III trial

IMFINZI plus IMJUDO combined with lenvatinib and transarterial chemoembolization (TACE) showed trend toward improved overall survival

WILMINGTON, Del.--(BUSINESS WIRE)-- Positive high-level results from the EMERALD-3 Phase III trial showed AstraZenecas IMFINZI® (durvalumab) in combination with IMJUDO® (tremelimumab-actl), lenvatinib and transarterial chemoembolization (TACE) demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint... More