Capricor reports positive HOPE-3 trial results for Duchenne therapy
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Capricor Therapeutics Announces Late-Breaking HOPE-3 Data at the 2026 MDA Conference Demonstrating Significant Functional Benefits of Deramiocel for Duchenne Muscular Dystrophy
March 12, 2026 9:01 AM EDTReduced progression of myocardial fibrosis measured by LGE on cardiac MRI (p=0.022)Significant improvement in LVEF versus placebo in patients with baseline cardiomyopathy (p=0.017)Global Statistical Test (GST) composite endpoint showed significant overall treatment benefitDuchenne Video Assessment (DVA) showed approximately 83% slowing of disease progression (p=0.018), consistent with mid-level (elbow) PUL v2.0 resultsDeramiocel BLA currently under FDA review with a PDUFA target action date of August 22, 2026
SAN DIEGO, March... More

