Spyre Therapeutics expects six trial readouts in 2026

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Spyre Therapeutics Poised for Transformational 2026 With Six Expected Proof-of-Concept Readouts Beginning in Q2

January 12, 2026 8:01 AM EST

6 in 26 expected proof-of-concept (POC) readouts across SKYLINE and SKYWAY trials

SKYLINE platform trial in ulcerative colitis (UC) recruiting faster than expected with SPY001 enrollment complete ahead of schedule; Part A readouts accelerated, now expected to start in Q2

SKYWAY basket trial enrollment on track across rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA); All readouts expected in 4Q 2026

Kate Tansey Chevlen appointed Chief Commercial Officer (CCO)

Strong balance sheet with pro forma cash, cash equivalents, and marketable securities balance of... More