Lilly reports four-year remission data for ulcerative colitis drug

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Lilly's Omvoh (mirikizumab-mrkz) is the first and only IL-23p19 antagonist to show four years of sustained, corticosteroid-free comprehensive patient outcomes in ulcerative colitis

October 7, 2025 6:45 AM EDT

Approximately 80% of Omvoh-treated patients in the LUCENT-3 study who achieved clinical remission at one year maintained long-term, corticosteroid-free clinical and endoscopic remission

At four years, nearly all patients who achieved clinical remission at one year had improvements in bowel urgency, one of the most disruptive symptoms for patients

INDIANAPOLIS, Oct. 7, 2025 /PRNewswire/ -- New data from Eli Lilly and... More