Praxis reports positive seizure reduction results from vormatrigine trial

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Praxis Precision Medicines Announces Positive, Best-in-Disease Topline Results in Patients with Focal Onset Seizures from the RADIANT Study of Vormatrigine

August 4, 2025 8:00 AM EDT

Dosing with vormatrigine over 8 weeks led to 56.3% median reduction in seizure frequency

Approximately 22% of patients reached 100% reduction in seizure frequency in the last 28 days on treatment

Rapid and sustained response, with over 54% of patients achieving 50% response in the first week

Vormatrigine was generally well tolerated and continues to demonstrate favorable safety profile

BOSTON, Aug. 04, 2025 (GLOBE NEWSWIRE) --... More