Janux Therapeutics (JANX) PT Raised to $115 at Stifel
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Janux Announces Doses Selected for Phase 1b Expansion Trials Supported by Encouraging Efficacy and Safety Profile Observed in Phase 1a Dose Escalation for JANX007 in mCRPC
December 2, 2024 4:30 PM ESTEmerging JANX007 data demonstrated substantial clinical activity in 5L mCRPC patients, supporting clinical development plan directed at pre-PLUVICTO® 2L / 3L patients In 16 patients JANX007 displayed: High PSA response rates: 100% achieved best PSA50 declines Deep PSA declines: 63% achieved best PSA90 declines; 31% achieved best PSA99 declines Durable PSA response at 12 weeks: 75% maintained PSA50 declines; 50% maintained PSA90 declines Encouraging anti-tumor activity: 50% ORR (4/8) and 63% DCR (5/8) Well-tolerated safety profile: CRS and TRAEs primarily limited to cycle 1 and grades 1 and 2; Maximum tolerable dose has not yet... More
