Verve Therapeutics (VERV) PT Lowered to $40 at Stifel

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Verve Therapeutics Announces Updates on its PCSK9 Program

April 2, 2024 7:00 AM EDT

Heart-1 clinical trial demonstrated LDL-C reduction of up to 73% at 0.45 mg/kg of VERVE-101

Company to pause enrollment in Heart-1 clinical trial following asymptomatic Grade 3 transient ALT elevation and thrombocytopenia seen in the sixth participant enrolled in 0.45 mg/kg dose cohort

Verve to prioritize development of VERVE-102, which uses a different LNP delivery system than VERVE-101; Clinical Trial Applications have been cleared by the U.K. MHRA and Health Canada; initiation of Heart-2 clinical trial of VERVE-102 is expected in 2Q 2024, consistent with existing PCSK9 program guidance

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