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Merck (MRK) STRIDE-3 Trial of V116 Vaccine Demonstrated Superior Immunogenicity vs PCV20 in Older Adults
November 28, 2023 6:48 AM ESTMerck (NYSE: MRK) announced results from STRIDE-3, a Phase 3 trial evaluating V116, the companys investigational 21-valent pneumococcal conjugate vaccine specifically designed to protect adults. The trial evaluated the immunogenicity, tolerability and safety of V116 compared to PCV20 (pneumococcal 20-valent conjugate vaccine) in adults who had not previously received a pneumococcal vaccine.
Results from the studys primary objectives include:
In adults 50 years of age and older (Cohort 1), V116 elicited non-inferior immune responses compared to PCV20 for all 10 serotypes common to both vaccines as measured by serotype-specific opsonophagocytic activity... More
