Selecta Biosciences (SELB) Misses Q3 EPS by 9c; Reports Cash and Cash Equivalents of $140.0M

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Selecta Biosciences (SELB) Announces Top Line Data from Phase I SEL-399 AAV Empty Capsid Study, Highlighting Potential Benefits of ImmTOR in Gene Therapy

November 8, 2021 8:13 AM EST

Selecta Biosciences, Inc. (NASDAQ: SELB), a biotechnology company leveraging its ImmTOR platform to develop tolerogenic therapies that selectively mitigate unwanted immune responses, today announced top-line results from a joint Selecta and AskBio Phase I randomized, placebo controlled, double blind, dose-escalation study to evaluate the potential of its ImmTOR platform in mitigating the formation of neutralizing antibodies against an adeno-associated viral serotype 8 (AAV8) serotype capsid used in gene therapies. At day 30, in those subjects administered a single 0.3 mg/kg dose of ImmTOR, Selecta observed a median anti-AAV8 neutralizing antibody titer of 1:5, a 250-fold lower level... More