Vertex Pharma (VRTX) Tops Q1 EPS by 72c, Revenues Beat; Raises FY20 Revenues Guidance

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Vertex Pharma (VRTX) Granted European CHMP Positive Opinion for KALYDECO for Children/Adolescents with CF and R117H Mutation in CFTR Gene

May 1, 2020 5:50 AM EDT

Vertex Pharmaceuticals Incorporated (NASDAQ: VRTX) today announced that the European Medicines Agencys (EMA) Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion for the label extension of KALYDECO® (ivacaftor), to include the treatment of children and adolescents with cystic fibrosis (CF), ages 6 months and older weighing at least 5 kg who have the R117H mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

Todays announcement is important for young people with CF, as early intervention and treatment of this devastating and progressive disease is key to... More

RBC Capital Downgrades Vertex (VRTX) to Sector Perform

April 28, 2020 5:12 AM EDT

RBC Capital analyst Brian Abrahams downgraded Vertex (NASDAQ: VRTX) from Outperform to Sector Perform with a price target of $260.00 (from $250.00).

The analyst comments "We remain bullish on the company's fundamentals, with high growth prospects for its core cystic fibrosis franchise, strong adoption of launching drug Trikafta, good insulation from COVID-19 likely... More

Vertex Pharma (VRTX), Affinia Therapeutics Establish Multi-Year Collaboration to Discover and Develop Novel AAV Capsids for Genetic Therapies

April 27, 2020 8:32 AM EDT

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Affinia Therapeutics announced today that the two companies have entered into a strategic research collaboration to engineer novel adeno-associated virus (AAV) capsids to deliver transformative genetic therapies to people with serious diseases. Affinia Therapeutics proprietary AAVSmartLibrary and associated technology provides capsids for improved tissue tropism, manufacturability and pre-existing immunity. The collaboration will leverage Affinia Therapeutics capsid engineering expertise and Vertexs scientific, clinical and regulatory capabilities to accelerate the development of genetic therapies for people affected by Duchenne muscular dystrophy (DMD), myotonic dystrophy type 1 (DM1) and cystic fibrosis (CF).

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