Halozyme Announces Actions To Focus Strategy On ENHANZE® Drug Delivery Technology

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Halozyme Therapeutics (HALO) to Resume Trading at 7:30 am

November 4, 2019 7:19 AM EST

Halozyme Therapeutics (NASDAQ: HALO) to Resume Trading at 7:30 am

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Halozyme Therapeutics (HALO) Reports HALO-301 Phase 3 Study Fails To Meet Primary Endpoint

November 4, 2019 7:03 AM EST

Halozyme Therapeutics, Inc. (NASDAQ: HALO) today announced that the HALO-301 Phase 3 clinical study evaluating investigational new drug PEGPH20 as a first-line therapy for treatment of patients with metastatic pancreas cancer failed to reach the primary endpoint of overall survival.

The treatment arm of PEGPH20 in combination with gemcitabine and nab-paclitaxel (ABRAXANE®) failed to demonstrate an improvement in median overall survival compared to gemcitabine and nab-paclitaxel alone (11.2 months compared to 11.5 months, HR=1.00, p=0.9692). While there was a higher response rate in the PEGPH20 treatment arm, this did not translate into an improvement in... More