Cytokinetics (CYTK) Tops Q4 EPS by 4c, Revenues Beat; Offers FY19 Revenue Mid-Point Guidance Above Consensus
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Amgen (AMGN) Cytokinetics (CYTK) & Servier Report Start of METEORIC-HF, the Second Phase 3 Clinical Trial Of Omecamtiv Mecarbil In Patients with Heart Failure
February 21, 2019 8:37 AM ESTAmgen (NASDAQ: AMGN), Cytokinetics, Incorporated (NASDAQ: CYTK) and Servier today announced that METEORIC-HF (Multicenter Exercise Tolerance Evaluation of Omecamtiv Mecarbil Related to Increased Contractility in Heart Failure), the second Phase 3 clinical trial of omecamtiv mecarbil, a novel cardiac myosin activator, is open to enrollment. Omecamtiv mecarbil is being developed for the potential treatment of heart failure with reduced ejection fraction (HFrEF).
METEORIC-HF is designed to evaluate the effect of treatment with omecamtiv mecarbil compared to... More
Cytokinetics (CYTK) Commences Phase 1 Clinical Study of AMG 594
February 20, 2019 9:02 AM ESTCytokinetics, Incorporated (NASDAQ: CYTK) today announced that the first subject has been dosed in a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of AMG 594 in healthy subjects. AMG 594 is a cardiac troponin activator, discovered under a joint research program conducted between Amgen and Cytokinetics. The study is being conducted by Amgen in collaboration with Cytokinetics.
The initiation of this Phase 1 study of AMG 594 further reflects the... More

