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RXI Pharma (RXII) Announces Research Collaboration with Karolinska Institutet to Develop d-rxRNA Compounds to Improve Functionality & Persistence of T Cells & NK Cells

August 15, 2018 9:27 AM EDT

RXi Pharmaceuticals Corporation (NASDAQ: RXII) today announced that it has entered into a research collaboration with the Karolinska Institutet in Stockholm, Sweden. This collaboration will explore RXi's sd-rxRNA compounds against targets involved in T cell and NK cell differentiation and/or in the immune cell tumor-induced stress response with the aim of producing anti-tumor adoptive cell therapy grafts with improved functionality and persistence.

This work will expand on the recently published results from the Kiessling group demonstrating that an sd-rxRNA targeting PD-1 can enhance TIL antitumor activity against melanoma cells in... More