Spark Therapeutics (ONCE) PT Lowered to $61 at SunTrust Robinson Humphrey

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Spark Therapeutics Reports Second Quarter 2018 Financial Results and Recent Business Progress

August 7, 2018 7:30 AM EDT

As of July 13, 2018, preliminary Phase 1/2 data for investigational SPK-8011 for hemophilia A show:

A 97-percent reduction in annualized bleeding rate (ABR) and 97-percent reduction in annualized infusion rate (AIR) across all 12 participants in the studyEvidence of stable, durable expression, with no decline in plateau FVIII levels, in both participants in the 5x1011 vg/kg cohort who have been followed for greater than one year A dose response as demonstrated by FVIII expression ranging from 16 to 49 percent, with a mean of 30 percent post... More