Ionis Pharmaceuticals Provides Update on IONIS-TTR Rx Program

BMO Capital Downgrades Ionis Pharmaceuticals (IONS) to Market Perform

BMO Capital downgraded Ionis Pharmaceuticals (NASDAQ: IONS) from Outperform to Market Perform with a price target of $26.00 (from $55.00).

Analyst Do Kim commented, "We are downgrading IONS shares to Market Perform from Outperform, following partner GSKs decision to delay the CARDIO-TTR Phase III... More

Needham & Company Cut PT, But Keeps 'Buy' on Ionis Pharmaceuticals (IONS) Amid Update

Needham & Company analyst Chad Messer is sticking with his Buy rating but reducing his target to $55 (from $88) on Ionis Pharmaceuticals (NASDAQ: IONS) after Ionis announced that partner GSK is delaying its decision to initiate that study until after NEURO-TTR reads out in 1H:17. Severe thrombocytopenia... More

Leerink Remains Cautious on Ionis Pharmaceuticals (IONS) Following Conference Call

Leerink Partners analyst Michael Schmidt weighed in on Ionis Pharmaceuticals (NASDAQ: IONS) after the company held a conference call this morning to discuss GSK's decision not to initiate the planned "CARDIO-TTR" Phase III trial of IONS-TTR-Rx in patients with TTR amyloid cardiomyopathy (FAC).

Schmidt notes this decision... More

Cowen Downgrades Ionis Pharmaceuticals (IONS) to Market Perform

Cowen downgraded Ionis Pharmaceuticals (NASDAQ: IONS) from Outperform to Market Perform.

For an analyst ratings summary and ratings history on Ionis Pharmaceuticals click here. For more ratings news on Ionis Pharmaceuticals click here.

Shares of Ionis Pharmaceuticals closed at $35.26 yesterday.

Alnylam Pharma (ALNY) Gains on Ionis (IONS) Setback

Alnylam Pharma (NASDAQ: ALNY) is gaining sharply Thursday (11.9%), related to a setback for Ionis Pharmaceuticals's (Nasdaq: IONS) IONIS-TTRRx program. Ionis' partner GSK has decided not to initiate a Phase 3 outcome study, CARDIO-TTR, which was planned to evaluate IONIS-TTRRx in patients with TTR amyloid cardiomyopathy. IONS is down 32%.

Ionis Pharma (IONS): CARDIO-TTR Trial Uncertainty as GSK Stops Initiation - BMO

BMO Capital Markets analyst, Do Kim, notes that Ionis Pharmaceuticals (NASDAQ: IONS) partner GSK will not initiate the CARDIO-TTR Phase III trial, following the FDA clinical hold related to patient safety monitoring in the study design. He believes that the study is probably... More