Medivation Announces Presentation of Phase I Talazoparib Combination Data in Several Advanced Cancers

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Medivation (MDVN) Preclinical Excitement Seems To Be Bearing Fruit - Stifel

April 18, 2016 9:59 AM EDT

Stifel analyst, Thomas Shrader, thinks that preclinical excitement for Medivation's (NASDAQ: MDVN) talazoparib is bearing fruit. Much of Medivations excitement in Talazoparib is based on the drugs ability to trap the PARP enzyme on the DNA and act like a Topo II inhibitor in addition to inhibiting PARP enzymatic activity. Topo II inhibitors from the anthracycline family are the most broadly active drugs... More